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Equity Securities Without Readily Determinable Fair Value, Impairment or Price Adjustment Amount Adjustments to value of investment in equity securities Document Transition Report Document Transition Report Share-Based Compensation Arrangement by Share-Based Payment Award, Purchase Price of Common Stock, Percent Percentage of fair market value of common stock Lessee, Operating Lease, Liability, to be Paid, Year Two Operating Lease Payments, 2026 Valuation Approach and Technique [Domain] Valuation Approach and Technique Antidilutive Security, Excluded EPS Calculation [Table] Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table] Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price Weighted-average exercise price, Exercised Auditor Firm ID Minimum [Member] Minimum Common Stock [Member] Common Stock Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value Weighted average grant date fair value, Nonvested at December 31, 2021 Weighted-average grant date fair value, Nonvested at December 31, 2022 Deferred tax assets, operating lease liabilities. Deferred Tax Assets Operating Lease Liabilities Operating lease liabilities Additional Paid-in Capital [Member] Additional Paid-in Capital Entity Well-known Seasoned Issuer Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract] Adjustments to reconcile net loss to net cash used in operating activities: Short-Term Investments Short-Term Investments [Member] Statement of Income Location, Balance [Domain] Income Statement Location Lessee, Operating Lease, Liability, to be Paid, Year One Operating Lease Payments, 2025 Lessor, Operating lease existence of option to extend [true false] Lessor, Operating Lease, Existence of Option to Extend [true false] Other Assets, Noncurrent, Total Other Assets, Noncurrent Other assets Black-Scholes Option Pricing Model [Member] Black-Scholes option pricing model. Black-Scholes option pricing model Share-based payment arrangement, withheld on behalf of employees for future purchase. Share-based Payment Arrangement, Withheld on Behalf of Employees for Future Purchase Share-based payment arrangement, withheld on behalf of employees for future purchase Entity Common Stock, Shares Outstanding Loss Contingency, Number of Plaintiffs Number of litigations filed Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, Less than 12 Months Unrealized losses less than 12 months, Fair value Katmai Pharmaceuticals, Inc. Katmai Pharmaceuticals Incorporation [Member] Katmai Pharmaceuticals, Inc. 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Issuance Of Common Stock In Connection With Asset Acquisition Issuance of common stock in connection with asset acquisition Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, 12 Months or Longer, Accumulated Loss Unrealized Losses 12 months or Greater, Unrealized Losses Unrealized losses 12 months or greater, Unrealized losses Weighted Average Number of Shares Outstanding, Diluted, Total Weighted Average Number of Shares Outstanding, Diluted Weighted-average shares of common stock used in computing net loss per share, diluted Significant Accounting Policies [Text Block] Summary of Significant Accounting Policies Research and Development Expense (Excluding Acquired in Process Cost) Research and development Lessee, Operating Lease, Liability, to be Paid Total lease payments Operating lease, aggregate monthly payments to lessor Cybersecurity Risk Management Third Party Engaged [Flag] ATM Offering At The Market Offering [Member] At The Market offering. Foreign Income Tax Expense (Benefit), Continuing Operations, Total Foreign Income Tax Expense (Benefit), Continuing Operations Provision for foreign income taxes Entity Small Business Entity Small Business Segment Reporting Information [Line Items] Cybersecurity Risk Management Processes for Assessing, Identifying, and Managing Threats [Text Block] Increase decrease in accrued expenses and other current and long-term liabilities. Increase Decrease In Accrued Expenses And Other Current And Long-term Liabilities Accrued expenses and other current and long-term liabilities Charges in Connection with Reduction in Force Charges in connection with reduction in force. 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